Projects are the primary way different jobs are categorized. Your company can have multiple projects, with Activities assigned to each project.
To make a new project, click the "Add New Project" card on the project screen.
This will open the New Project menu. Continue by completing the fields of information.
The Timezone of the project is important (and required) as it allows the Core system to properly sync the Start Dates and Due Dates of Activities with the correct timezone for that project.